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KMID : 0545120040140010148
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Journal of Microbiology and Biotechnology
2004 Volume.14 No. 1 p.148 ~ p.152
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Antagonistic Activity of Polyfermenticin SCD Against Helicobacter pylori KCTC 2948
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KIM, SEONG-MI
LEE, KWANG-HO/LEE, NA-KYOUNG/KIM, CHEON-JEI/KIM, CHANG-HAN/PAIK, HYUN-DONG
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Abstract
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Bacillus polyfermenticus SCD and polyfermenticin SCD, named tentativelsy as the bacteriocin produced by B. polyfermenticus SCD, showed antimicrobial activity aganist Helicobacter pylori KCTC 2948 growth. When crude polyfermenticin SCD was added to the growing H. pylori cells, viable cell numbers were reduced, indicating antimicrobial action. The antimicrobial effect was increased remarkably at higher concentrations of polyfermenticin SCD and longer exposure. Morphological changes were observed in the bacteriocin-treated cells : in the exponential phase, they appeared as shrunken rods, while in the sationary phase, they showed coccoid forms.
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